Indiziert in
- Öffnen Sie das J-Tor
- Genamics JournalSeek
- Akademische Schlüssel
- JournalTOCs
- Nationale Wissensinfrastruktur Chinas (CNKI)
- Ulrichs Zeitschriftenverzeichnis
- RefSeek
- Hamdard-Universität
- EBSCO AZ
- Verzeichnis der Abstract-Indexierung für Zeitschriften
- OCLC – WorldCat
- Publons
- Genfer Stiftung für medizinische Ausbildung und Forschung
- Euro-Pub
- Google Scholar
Nützliche Links
Teile diese Seite
Zeitschriftenflyer
Open-Access-Zeitschriften
- Allgemeine Wissenschaft
- Biochemie
- Bioinformatik und Systembiologie
- Chemie
- Genetik und Molekularbiologie
- Immunologie und Mikrobiologie
- Klinische Wissenschaften
- Krankenpflege und Gesundheitsfürsorge
- Landwirtschaft und Aquakultur
- Lebensmittel & Ernährung
- Maschinenbau
- Materialwissenschaften
- Medizinische Wissenschaften
- Neurowissenschaften und Psychologie
- Pharmazeutische Wissenschaften
- Umweltwissenschaften
- Veterinärwissenschaften
- Wirtschaft & Management
Abstrakt
Stem Cells Therapy in Diabetes Mellitus
Yang Xi and Shizhong Bu
Diabetes is one of the top 10 leading causes of morbidity and mortality, affecting nearly 350 million people worldwide. β-cell replacement represents an attractive prospect for diabetes therapy but treatment options remain quite limited. There is increasing hope placed on insulin producing cells derived from human pluripotent stem cells, even as the approach faces continued challenges. The most effective protocols thus far have produced cells that express insulin, and have molecular characteristics that closely resemble genuine insulin-secreting cells. However, these cells demonstrate little sensitivity to glucose – an issue that will hopefully be resolved in coming years. This review summarizes recent progress in obtaining cells that express insulin from different progenitor sources, and highlights the major pathways and genes involved in diabetic patients.