Zeitschrift für Stammzellforschung und -therapie

Abstrakt

How to Maximize the Success of Stem Cell Autografts for Neuroregeneration

Nassim H Abi Chahine, Elie S Abou Saad and Saade Gibran E Melki

Over a period of five years, two hundred patients with degenerative chronic neurological disorders were monitored after the treatment with adult autologous bone marrow derived stem cells. Our field of study covered a wide range of diseases and multiple protocols were explored. Autologous bone marrow derived stem cells were outsourcing all the procedures. Several steps forward have been achieved. We notably worked on the grounding of patients, stem cells proliferation and processing. We described the decant effect, the ultimate incubation modes, the optimal way of filtration and the active homing phenomena related to cytokines released from the injured zone. We also worked on the techniques of transplantation during the injections. Furthermore this article talks about The First Show Phenomenon and many other symptoms facilitating the understanding of autologous stem cell treatments. Our field of study also covered stem cells clustering, the antibiotic effect on newly transplanted cells, and the implication of Mannitol in neuroregeneration, the role of detoxification before ASCT (Autologous stem cell transplantation) in Amyotrophic lateral sclerosis (ALS), the effect of Jugular treatment before ASCT in Multiple Sclerosis. This article promises big changes in many cardinal steps: The importance of ASCT in spinal cord injuries, the role of hyperbaric chamber and adrenal regeneration. We will finally present our work in the field of nanomedicine with its peptides as a supportive tool in order to strengthen the success of our treatment.
We concluded that Time is after-all, the crucial element that defines the percentage of success; it is the superlative condition for regeneration. Patients treated early showed firmly better improvement.