Abstrakt

R-Spondin 1 regulates the WNT signaling pathway by antagonizing the function of Dickkopf homolog 1

Yang Wang, Bingqiang Zhang and Wei Zou

The WNT family of secreted proteins plays an important role in various biological processes, including development, proliferation and differentiation, and regulates various diseases such as prostate cancer, breast cancer, glioblastoma, type II diabetes and others. The WNT ligands could activate two important intracellular signaling pathways: the so-called canonical signaling pathway, which is β-catenin-dependent, and the non-canonical signaling pathway, which is β-catenin-independent.

Haftungsausschluss: Dieser Abstract wurde mit Hilfe von Künstlicher Intelligenz übersetzt und wurde noch nicht überprüft oder verifiziert.