Zeitschrift für Neonatalbiologie

Abstrakt

Non-restrictive ductal patency in the treatment of heart failure in congenital diaphragmatic hernia – non-invasive biventricular support

Abhay Divekar, Mary M Seshia and Murray Kesselman

Pulmonary vascular resistance (PVR) is increased to some degree in all patients with congenital diaphragmatic hernia (CDH). In patients with severely increased PVR, closure or restriction of a previously patent ductus arteriosus (PDA) can lead to hemodynamic compromise secondary to acute heart failure. Maintaining patency of the ductus arteriosus is not a well-established therapeutic strategy in this patient population. This report examines the potential benefit of maintaining patency of the ductus arteriosus by discussing the pathophysiology and reviewing the published literature.