Ashish Jain, Vivek Khanna, Veeraraja Basavanthappa Sathenahalli and Vivek Khurana
Neonatal herpes simplex virus (HSV) infection is a vertically transmitted infection that is passed from the mother to the baby before or during delivery and also through infected secretions after birth. The incidence varies worldwide from 1:3200 to 1:60000 births. Untreated infections are often life-threatening. It should be considered as a differential diagnosis in a febrile infant less than one month of age with risk factors. Definitive culture or polymerase chain reactions are used for diagnosis. Treatment consists of antiviral therapy with acyclovir. Early diagnosis and prompt treatment reduce associated morbidity and mortality. Here, we report a case of neonatal herpes simplex virus infection that was diagnosed early and effectively treated with acyclovir.