Indiziert in
- Öffnen Sie das J-Tor
- Genamics JournalSeek
- CiteFactor
- RefSeek
- Hamdard-Universität
- EBSCO AZ
- NSD – Norwegisches Zentrum für Forschungsdaten
- OCLC – WorldCat
- Publons
- Genfer Stiftung für medizinische Ausbildung und Forschung
- Euro-Pub
- Google Scholar
Nützliche Links
Teile diese Seite
Zeitschriftenflyer
Open-Access-Zeitschriften
- Allgemeine Wissenschaft
- Biochemie
- Bioinformatik und Systembiologie
- Chemie
- Genetik und Molekularbiologie
- Immunologie und Mikrobiologie
- Klinische Wissenschaften
- Krankenpflege und Gesundheitsfürsorge
- Landwirtschaft und Aquakultur
- Lebensmittel & Ernährung
- Maschinenbau
- Materialwissenschaften
- Medizinische Wissenschaften
- Neurowissenschaften und Psychologie
- Pharmazeutische Wissenschaften
- Umweltwissenschaften
- Veterinärwissenschaften
- Wirtschaft & Management
Abstrakt
Is Osteoarthritis of the Knee Hereditary? A Review of the Literature
Clement ND
Osteoarthritis (OA) of the knee joint is a common cause of disability. This review presents the current evidence and knowledge regarding the genetic inheritability of OA of the knee, and a contemporary hypothesis for progression of the disease. The current evidence would suggest there is a hereditary predisposition to OA of the knee. However, this would seem to be multifactorial and the development of OA in the knee may depend upon multiple genetic factors, not only of those relating to cartilage degeneration but also of those relating to the morphology of the knee joint, both of these factors seem to be influenced by similar genes. Knowledge of these genes that affect the initiation and/ or progression of knee OA are important for development of new treatment options at an early stage of the disease preventing future physical disability.