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Abstrakt
Integrated Application of Bioprocess Engineering and Biotechniques for Quality & Bulk Drug Manufacturing
Atanu Kumar Jena, D K Mahalakshmi and G Sridhari
One of the major challenges facing the pharmaceutical industry today is finding new ways to increase productivity, decrease costs whilst still ultimately developing new therapies that enhance human health. Both Biotechniques & Bioprocess engineering are integrated for bulk drug manufacturing of biopharmaceutical products to outcome the above problem. Different biotechnological processes are used in industries for large scale production of biological products for optimization of yield and the quality of end product. Various recent developments in biotechniques and its collaborated work with bioprocess engineering helps to maintain the quality in manufacturing process. However in this review article, we systemically describe all the techniques and different bioprocess used for manufacturing of drugs. To the author’s knowledge this review represents the most exhaust description of different biotechniques, different bioprocess, process development and design criteria in bioprocess.