Indiziert in
- Öffnen Sie das J-Tor
- Genamics JournalSeek
- CiteFactor
- Kosmos IF
- Scimago
- Ulrichs Zeitschriftenverzeichnis
- Elektronische Zeitschriftenbibliothek
- RefSeek
- Hamdard-Universität
- EBSCO AZ
- Verzeichnis der Abstract-Indexierung für Zeitschriften
- OCLC – WorldCat
- Proquest-Vorladungen
- Gelehrtersteer
- STRASSE
- Virtuelle Bibliothek für Biologie (vifabio)
- Publons
- Genfer Stiftung für medizinische Ausbildung und Forschung
- Google Scholar
Nützliche Links
Teile diese Seite
Zeitschriftenflyer
Open-Access-Zeitschriften
- Allgemeine Wissenschaft
- Biochemie
- Bioinformatik und Systembiologie
- Chemie
- Genetik und Molekularbiologie
- Immunologie und Mikrobiologie
- Klinische Wissenschaften
- Krankenpflege und Gesundheitsfürsorge
- Landwirtschaft und Aquakultur
- Lebensmittel & Ernährung
- Maschinenbau
- Materialwissenschaften
- Medizinische Wissenschaften
- Neurowissenschaften und Psychologie
- Pharmazeutische Wissenschaften
- Umweltwissenschaften
- Veterinärwissenschaften
- Wirtschaft & Management
Abstrakt
Immunosuppression Induced by HIV Infection
Mohamed G Elfaki
Immunosuppression due to HIV infection is a resultant of several factors including defective innate signaling pathways, increased viral replication and virus load, gradual loss of peripheral CD4+T cells and depletion of T lymphocytes at mucosal sites that collectively lead to progressive immune deficiency and AIDS development. T cells derived from HIV patients were anergic and failed to mount a robust adaptive immune response. The host, on the other hand, becomes vulnerable to opportunistic infections such as tuberculosis and AIDS-related cancer such as Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer with remarkable level of immunosuppression. Elucidation of the various mechanisms involved in these immunologic perturbations is necessary to understand HIV pathogenesis for an effective immunotherapy.