Einzelzellbiologie

Abstrakt

Centrosome centering and decentering by rearrangement of the microtubule network

Gaëlle Letort and Mithila Burute

Seeing is believing, but not necessarily understanding. Advances in microscopy have allowed us to observe cellular mechanisms at work. For example, sequences of events imaged during cell division revealed important changes in the cytoskeleton and shape of the cell. Understanding how the forces that drive spindle pole movement are balanced during cell division requires additional adjustments to the system beyond mere observations. Elegant experimental setups such as laser microsurgery or optical tweezers can be used to identify components of the force balance.